Targeted survival improvements in clinical trials: Are you an absolutist or relativist?
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Targeted survival improvements in clinical trials: Are you an absolutist or relativist?
The design of a clinical trial is a complex business that requires careful consideration of several factors, with one of the most crucial being the assessment of the targeted improvement in the primary outcome measure, which is also one of the principal determinants of sample size. The article by Castonguay et al in the current issue of Cancer reviews the accuracy with which the median progress...
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ژورنال
عنوان ژورنال: Cancer
سال: 2014
ISSN: 0008-543X
DOI: 10.1002/cncr.29031